Estrogen Receptor alpha Antikörper (AA 1-21)

Produktnummer ABIN215829

Der Kaninchen Polyklonal anti-Estrogen Receptor alpha Antikörper (ABIN215829) detektiert spezifisch Estrogen Receptor alpha in WB, IHC, IHC (p), ICC und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Affe, Pferd und Hamster.

Kurzübersicht für Estrogen Receptor alpha Antikörper (AA 1-21) (ABIN215829)

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Affe, Pferd, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Estrogen Receptor alpha Antikörper

Bindungsspezifität: AA 1-21

Spezifität: Recognizes human and rat endogenous ER alpha. Detects a band of ~64kD by Western blot. Does not cross-react with ER beta. This sequence is completely conserved in rat and mouse ER alpha and is highly conserved in sheep, porcine, canine, bovine and chicken ER alpha.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Tamarin, Mouse, Rat, Hamster, Cat, Rabbit, Horse (100%) Panda, Bovine, Pig (95%) Sheep, Opossum (90%) Turkey, Chicken (86%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to aa 1-21 (M1TMTLHTKASGMALLHQIQGN21) of N-terminal human ER (estrogen receptor ). This sequence is completely conserved in rat and mouse ER and is highly conserved in sheep, pig, dog, bovine and chicken ER. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Tamarin, Mouse, Rat, Hamster, Cat, Rabbit, Horse (100%), Panda, Bovine, Pig (95%), Sheep, Opossum (90%), Turkey, Chicken (86%).

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ICC, IHC, IHC-Fr, IHC-P, WB (1 μg/mL)

Usage: Suitable for use in Immunocytochemistry, Immunohistochemistry and Western Blot. Immunohistochemistry (frozen, paraffin sections):1-5 μg/mL. Western Blot:1 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Epitope-affinity purified IgG in PBS, 1 mg/mL BSA, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C
Long term: -20°C.

Details zu Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: ER Alpha / Estrogen Receptor

Hintergrund: Name/Gene ID: ESR1
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha

Gen-ID: 2099

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly