Dopamine d2 Receptor Antikörper (3rd Cytoplasmic Domain)

Produktnummer ABIN215782

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Dopamine d2 Receptor in WB und ELISA. Er zeigt eine Reaktivität gegenüber Ratte und Hund.

Kurzübersicht für Dopamine d2 Receptor Antikörper (3rd Cytoplasmic Domain) (ABIN215782)

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reaktivität: Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dopamine d2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Dopamine d2 Receptor Antikörper

Bindungsspezifität: 3rd Cytoplasmic Domain

Spezifität: Recognizes rat Dopamine Receptor D2 long form. Recognizes canine D2R. Species sequence Homology: Human, bovine, and canine: 96 % , Xenopus: 64 %.

Aufreinigung: Immunoaffinity purified

Immunogen: A 27 amino acid peptide sequence from the rat D2 long form within the cytoplasmic loop #3. No significant homology with other receptors (D1, D2 short, and D3-D5).

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.5 - 1 μg/mL), WB (1 - 10 μg/mL)

Usage: Suitable for use in Western Blot and ELISA. Western Blot: 1-10 μg/mL (Chemiluminescence technique). The predicted size of D2L form is approximately 50kD. However, additional bands at approximately 60 and 100kD, and others are typically seen in various tissues. Approximately 100-400 μg of membrane protein/lane should be loaded to visualize various bands. ELISA: 0.5-1.0 μg/mL (1 μg/mL immunogen peptide/well).

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 100 mM Tris,  pH 7.5, 0.2 % BSA, 0.05 % sodium azide, 40 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Andere Bezeichnung: DRD2 / Dopamine Receptor D2

Hintergrund: Name/Gene ID: DRD2
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD2, D2 dopamine receptor, D2R, Dopamine receptor D2 isoform, Dopamine 2 receptor, D(2) dopamine receptor, D2DR, Dopamine D2 receptor, Dopamine receptor D2

Gen-ID: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity