Dopamine d2 Receptor Antikörper (3rd Cytoplasmic Domain)

Produktnummer ABIN215781

Produktdetails anti-Dopamine d2 Receptor Antikörper

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Bindungsspezifität: 3rd Cytoplasmic Domain

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dopamine d2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Spezifität: Specific for Dopamine Receptor D2 short and long form. Species cross-reactivity: Monkey, mouse and rat.

Aufreinigung: Affinity purified

Immunogen: A 28 amino acid peptide sequence from the human D2 receptor within the cytoplasmic loop #3. The immunogen peptide shows no significant homology with other dopamine receptors (D1 and D3-D5). Species sequence Homology: Bovine, canine - 100%, Xenopus - 50%.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.5 - 1 μg/mL), IHC, IP (1 - 10 μg/mL), WB (1:1000)

Usage: Suitable for use in Western Blot, Immunohistochemistry, Immunoprecipitation and ELISA. Western Blot: 1:1000. Detected Dopamine Receptor D2 on 10 μg of human brain lysates. Immunohistochemistry (Paraformaldehyde fixed sections): 2-10 μg/mL. Immunoprecipitation: 1-10 μg/mL. Using 100-400 μg of protein. An antibody made to this epitope has been shown to immunoprecipitate both the long and short forms. ELISA: 0.5-1.0 μg/mL. Positive control: Monkey brain tissue, rat brain lysate.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % BSA.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Andere Bezeichnung: DRD2 / Dopamine Receptor D2 (DRD2 Produkte)

Synonyme: D2DR antikoerper, D2R antikoerper, drd2b antikoerper, d2r2 antikoerper, Drd-2 antikoerper, d2dr antikoerper, d2r antikoerper, drd2 antikoerper, drd2-B antikoerper, DRD2 antikoerper, D2 antikoerper, CG18741 antikoerper, CG7569 antikoerper, DAMB antikoerper, DDR2 antikoerper, DOPR2 antikoerper, DOPR99B antikoerper, Dar2 antikoerper, Dmel\\CG18741 antikoerper, DopD1 antikoerper, DopR99B antikoerper, DopRII antikoerper, dopamine receptor D2 antikoerper, dopamine receptor D2 like antikoerper, dopamine receptor D2 L homeolog antikoerper, dopamine receptor D2 S homeolog antikoerper, Dopamine 1-like receptor 2 antikoerper, DRD2 antikoerper, drd2l antikoerper, drd2 antikoerper, Drd2 antikoerper, drd2.L antikoerper, drd2.S antikoerper, Dop1R2 antikoerper

Hintergrund: Name/Gene ID: DRD2
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD2, D2 dopamine receptor, D2R, Dopamine receptor D2 isoform, Dopamine 2 receptor, D(2) dopamine receptor, D2DR, Dopamine D2 receptor, Dopamine receptor D2

Gen-ID: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity