Dopamine d2 Receptor Antikörper (3rd Cytoplasmic Domain)

Produktnummer ABIN215781

Der Kaninchen Polyklonal anti-Dopamine d2 Receptor Antikörper (ABIN215781) detektiert spezifisch Dopamine d2 Receptor in WB, IHC, ELISA und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus und Affe.

Kurzübersicht für Dopamine d2 Receptor Antikörper (3rd Cytoplasmic Domain) (ABIN215781)

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dopamine d2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-Dopamine d2 Receptor Antikörper

Bindungsspezifität: 3rd Cytoplasmic Domain

Spezifität: Specific for Dopamine Receptor D2 short and long form. Species cross-reactivity: Monkey, mouse and rat.

Aufreinigung: Affinity purified

Immunogen: A 28 amino acid peptide sequence from the human D2 receptor within the cytoplasmic loop #3. The immunogen peptide shows no significant homology with other dopamine receptors (D1 and D3-D5). Species sequence Homology: Bovine, canine - 100%, Xenopus - 50%.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.5 - 1 μg/mL), IHC, IP (1 - 10 μg/mL), WB (1:1000)

Usage: Suitable for use in Western Blot, Immunohistochemistry, Immunoprecipitation and ELISA. Western Blot: 1:1000. Detected Dopamine Receptor D2 on 10 μg of human brain lysates. Immunohistochemistry (Paraformaldehyde fixed sections): 2-10 μg/mL. Immunoprecipitation: 1-10 μg/mL. Using 100-400 μg of protein. An antibody made to this epitope has been shown to immunoprecipitate both the long and short forms. ELISA: 0.5-1.0 μg/mL. Positive control: Monkey brain tissue, rat brain lysate.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % BSA.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Andere Bezeichnung: DRD2 / Dopamine Receptor D2

Hintergrund: Name/Gene ID: DRD2
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD2, D2 dopamine receptor, D2R, Dopamine receptor D2 isoform, Dopamine 2 receptor, D(2) dopamine receptor, D2DR, Dopamine D2 receptor, Dopamine receptor D2

Gen-ID: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity