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Estrogen Receptor alpha Antikörper (pSer104, Ser106)

Dieser Anti-Estrogen Receptor alpha Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Estrogen Receptor alpha in IHC, ELISA und IHC (p). Geeignet für Human.
Produktnummer ABIN214644

Kurzübersicht für Estrogen Receptor alpha Antikörper (pSer104, Ser106) (ABIN214644)

Target

Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reaktivität

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Human

Wirt

  • 406
  • 160
  • 1
Kaninchen

Klonalität

  • 349
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  • 1
Polyklonal

Konjugat

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Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation

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Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 34
    • 32
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    pSer104, Ser106

    Spezifität

    Peptide surrounding pSer 104 and pSer 106 of human ESR1

    Aufreinigung

    Protein G purified

    Immunogen

    Synthetic peptide from human ESR1 / Estrogen receptor.

    Type of Immunogen: Synthetic peptide
  • Applikationshinweise

    Approved: ELISA (1:1000), IHC, IHC-P (10 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

    Kommentare

    Target Species of Antibody: Human

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    PBS, 0.1 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    Andere Bezeichnung

    ER Alpha / Estrogen Receptor

    Hintergrund

    Name/Gene ID: ESR1
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha

    Gen-ID

    2099

    UniProt

    P03372

    Pathways

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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