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CD81 Antikörper

CD81 Reaktivität: Maus FACS Wirt: Hamster Monoclonal Eat2 unconjugated

Produktnummer ABIN212888

Datenblatt (PDF)

Target Alle CD81 Antikörper anzeigen

CD81
Reaktivität
133

96

44

18

17

9

9

5

3

2

1

1

1

1
Maus
Wirt
74

65

33

6

3

1
Hamster
Klonalität
128

48

3
Monoklonal
Konjugat
81

21

17

15

7

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD81 Antikörper ist unkonjugiert
Applikation
128

87

48

43

33

31

30

29

17

14

13

13

5

4

3

3

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and non-killer cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells.

Aufreinigung

Protein G purified

Immunogen

Type of Immunogen: Native protein

Klon

Eat2

Isotyp

IgG1

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Kommentare

Target Species of Antibody: Mouse

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS, 0.02 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
Target

CD81

Andere Bezeichnung

CD81 (CD81 Produkte)

Hintergrund

Name/Gene ID: CD81
Family: Tetraspan

Synonyms: CD81, CD81 antigen, CD81 Molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28

Gen-ID

975

UniProt

P60033

Pathways

Inositol Metabolic Process, Hepatitis C