CD81 Antikörper

Produktnummer ABIN212888

Der Hamster Monoklonal Anti-CD81-Antikörper wurde für FACS validiert. Er ist geeignet, CD81 in Proben von Maus zu detektieren.

Kurzübersicht für CD81 Antikörper (ABIN212888)

Target: CD81

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: Eat2

Produktdetails anti-CD81 Antikörper

Spezifität: Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and non-killer cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells.

Aufreinigung: Protein G purified

Immunogen:

Type of Immunogen: Native protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81

Hintergrund: Name/Gene ID: CD81
Family: Tetraspan

Synonyms: CD81, CD81 antigen, CD81 Molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28

Gen-ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C