ICAM1 Antikörper

Produktnummer ABIN211782

Produktdetails anti-ICAM1 Antikörper

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reaktivität: Human, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Recognizes the D1 domain of ICAM-1. Reacts with the ICAM-1 antigen found in low levels on lymphocytes and strongly expressed on monocytes and granulocytes. This molecule is inducible to high levels by mitogenic lectins on lymphocytes and by IL-1 beta or IFN gamma on other cell types such as fibroblasts and endothelial cells. Detects an antigen of 90kD. Clone 84H10 has been reported to block ICAM1 mediated cellular adhesion and block binding of LFA-1 and P. falciparum to ICAM-1. Removal of sodium azide is recommended prior to use in functional assays - XXX recommend the use of EQU003 for this purpose.

Aufreinigung: Protein A purified

Immunogen: K562 cell line.

Type of Immunogen: Cells

Klon: 84H10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:1 - 1:10), IHC, IHC-Fr (1:20 - 1:50), IP

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.

Not recommended for: IHC-P

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Andere Bezeichnung: ICAM1 / CD54 (ICAM1 Produkte)

Synonyme: BB2 antikoerper, CD54 antikoerper, P3.58 antikoerper, Icam-1 antikoerper, Ly-47 antikoerper, MALA-2 antikoerper, ICAM antikoerper, ICAM-1 antikoerper, ICAM1 antikoerper, intercellular adhesion molecule 1 antikoerper, intercellular adhesion molecule-1 antikoerper, ICAM1 antikoerper, Icam1 antikoerper, ICAM-1 antikoerper

Substanzklasse: Viral Protein

Hintergrund: Name/Gene ID: ICAM1
Family: ICAM

Synonyms: ICAM1, BB2, CD54 antigen, CD54, ICAM-1, p3.58

Gen-ID: 3383

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling