ICAM1 Antikörper
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- Target Alle ICAM1 Antikörper anzeigen
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Reaktivität
- Human, Hund
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ICAM1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Recognizes the D1 domain of ICAM-1. Reacts with the ICAM-1 antigen found in low levels on lymphocytes and strongly expressed on monocytes and granulocytes. This molecule is inducible to high levels by mitogenic lectins on lymphocytes and by IL-1 beta or IFN gamma on other cell types such as fibroblasts and endothelial cells. Detects an antigen of 90kD. Clone 84H10 has been reported to block ICAM1 mediated cellular adhesion and block binding of LFA-1 and P. falciparum to ICAM-1. Removal of sodium azide is recommended prior to use in functional assays - XXX recommend the use of EQU003 for this purpose.
- Aufreinigung
- Protein A purified
- Immunogen
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K562 cell line.
Type of Immunogen: Cells - Klon
- 84H10
- Isotyp
- IgG1
- Top Product
- Discover our top product ICAM1 Primärantikörper
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- Applikationshinweise
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Approved: Flo (1:1 - 1:10), IHC, IHC-Fr (1:20 - 1:50), IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Not recommended for: IHC-P - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Andere Bezeichnung
- ICAM1 / CD54 (ICAM1 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
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Name/Gene ID: ICAM1
Family: ICAM
Synonyms: ICAM1, BB2, CD54 antigen, CD54, ICAM-1, p3.58 - Gen-ID
- 3383
- UniProt
- P05362
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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