Transferrin Antikörper (N-Term)

Produktnummer ABIN211539

Dieses Anti-Transferrin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Transferrin in ELISA, IF und Func. Geeignet für Human, Schwein und Kaninchen.

Kurzübersicht für Transferrin Antikörper (N-Term) (ABIN211539)

Target: Transferrin (TF)

Reaktivität: Human, Schwein, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Functional Studies (Func)

Produktdetails anti-Transferrin Antikörper

Bindungsspezifität: N-Term

Spezifität: Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognize receptor bound transferrin. Clone HTF-14 recognizes a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor Transferrin is a 77 kD plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.

Keine Kreuzreaktivität: Rind (Kuh), Schaf, Hund, Pferd

Aufreinigung: Protein A purified

Immunogen: Purified porcine transferrin ( N-TERMINAL ).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu Transferrin

Target: Transferrin (TF)

Andere Bezeichnung: TF / Transferrin

Hintergrund: Name/Gene ID: TF

Synonyms: TF, PRO1557, Serotransferrin, Siderophilin, TFQTL1, Beta-1 metal-binding globulin, Transferrin, PRO2086

Gen-ID: 7018

UniProt: P02787

Pathways: Transition Metal Ion Homeostasis