alpha Fetoprotein Antikörper
Kurzübersicht für alpha Fetoprotein Antikörper (ABIN210027)
Target
Alle alpha Fetoprotein (AFP) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes alpha fetoprotein (AFP), a member of the albuminoid superfamily. It is a 68kD plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults. Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down's syndrome. 4520-5306 does not cross-react with human albumin and other human serum proteins.
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Aufreinigung
- Ion exchange chromatography
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Immunogen
- Native, from fetal cord.
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Andere Bezeichnung
- AFP / alpha Fetoprotein
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Hintergrund
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Name/Gene ID: AFP
Synonyms: AFP, Alpha-1-fetoprotein, Alpha-fetoprotein, HPAFP, Alpha-fetoglobulin, FETA -
Gen-ID
- 174
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Pathways
- C21-Steroid Hormone Metabolic Process
Target
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