CD4 Antikörper

Produktnummer ABIN206939

Der Maus-Monoklonal Anti-CD4-Antikörper wurde für FACS, IP, Func, BR, Neut und Inhibition validiert. Er ist geeignet zum Nachweis von CD4 in Proben aus Human. }

Kurzübersicht für CD4 Antikörper (ABIN206939)

Target: CD4

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut), Blocking Antibody (Inhibition)

Klon: MEM-115

Produktdetails anti-CD4 Antikörper

Spezifität: Recognizes an epitope in the D1 domain of CD4 antigen, a 55 kD transmembrane glycoprotein expressed on a subset of T lymphocytes (helper T cells) and also on monocytes, tissue macrophages and granulocytes. It is negative in Western blotting even with non-reduced samples of cell lysates.

Aufreinigung: Protein A purified

Immunogen: Human thymocytes and T lymphocytes.

Type of Immunogen: Cells

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: Block, Flo, Func, Inhb, IP, Neut

Usage: Immunoprecipitation: excellent. Functional Application: The antibody MEM-115 blocks binding of HIV gp120 to CD4 Molecule and it also strongly inhibits CD4-MHC Class II interactions. Flow Cytometry: Recommended dilution - 3 μg/mL. Application notes:. Altho

Not recommended for: IHC-P

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris buffered saline (TBS), 15 mM sodium azide, approx,  pH 8.0.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Hintergrund: Name/Gene ID: CD4

Synonyms: CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 Molecule

Gen-ID: 920

UniProt: P01730

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events