Integrin beta 3 Antikörper (FITC)
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- Target Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
- Integrin beta 3 (ITGB3)
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Reaktivität
- Maus, Ratte
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 3 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Spezifität
- Recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
- Aufreinigung
- Protein G purified
- Immunogen
- Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
- Isotyp
- IgG
- Top Product
- Discover our top product ITGB3 Primärantikörper
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- Applikationshinweise
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Approved: Flo (1:1 - 1:10), IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. - Kommentare
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Target Species of Antibody: Mouse
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- Integrin beta 3 (ITGB3)
- Andere Bezeichnung
- ITGB3 / Integrin Beta 3 / CD61 (ITGB3 Produkte)
- Hintergrund
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Name/Gene ID: ITGB3
Family: Integrin
Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3 - Gen-ID
- 3690
- UniProt
- P05106
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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