CD56 Antikörper
Kurzübersicht für CD56 Antikörper (ABIN206684)
Target
Alle CD56 (NCAM1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Recognizes human neural cell adhesion molecule (NCAM), otherwise known as CD56. The CD56 Molecule is a cell surface glycoprotein which is expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180kD form, while hemopoietic cells express the 140kD isoform. Antibodies produced by clone 123C3 recognize the 140 and 180kD isoforms of the CD56 protein. In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. Studies suggest that CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumors including tumors of the lung, neural derived malignancies and natural killer cell lymphomas.
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Aufreinigung
- Protein G purified
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Immunogen
- Small cell lung carcinoma.
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Isotyp
- IgG1
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Applikationshinweise
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Approved: ELISA, Flo (1:10), IHC, IHC-Fr, IHC-P (1:200, 10 μg/mL)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Andere Bezeichnung
- NCAM / CD56
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Hintergrund
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Name/Gene ID: NCAM1
Family: Immunoglobulin
Synonyms: NCAM1, CD56, CD56 antigen, MSK39, NCAM-1, N-CAM-1, NCAM -
Gen-ID
- 4684
Target
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