L-Selectin Antikörper (FITC)
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- Target Alle L-Selectin (SELL) Antikörper anzeigen
- L-Selectin (SELL) (Selectin L (SELL))
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Reaktivität
- Human, Rind (Kuh), Cynomolgus, Rhesusaffen
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser L-Selectin Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Recognizes human CD62L, also known a L-selectin, a 74-95kD member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naA-ve lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
- Aufreinigung
- Protein G purified
- Immunogen
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PHA stimulated lymphoblasts.
Type of Immunogen: Cells - Klon
- FMC46
- Isotyp
- IgG2b
- Top Product
- Discover our top product SELL Primärantikörper
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- Applikationshinweise
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Approved: Flo (1:1), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- L-Selectin (SELL) (Selectin L (SELL))
- Andere Bezeichnung
- SELL / L-Selectin / CD62L (SELL Produkte)
- Synonyme
- CD62L antikoerper, LAM1 antikoerper, LECAM1 antikoerper, LEU8 antikoerper, LNHR antikoerper, LSEL antikoerper, LYAM1 antikoerper, PLNHR antikoerper, TQ1 antikoerper, A.11 antikoerper, L-selectin antikoerper, LECAM-1 antikoerper, SELE antikoerper, AI528707 antikoerper, Lnhr antikoerper, Ly-22 antikoerper, Ly-m22 antikoerper, Lyam-1 antikoerper, Lyam1 antikoerper, selectin L antikoerper, selectin, lymphocyte antikoerper, SELL antikoerper, Sell antikoerper
- Substanzklasse
- Chemical
- Hintergrund
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Name/Gene ID: SELL
Synonyms: SELL, CD62L, CD62L antigen, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Lyam-1, LSEL, gp90-MEL, HLHRc, PLNHR, L-selectin, Leu-8, Selectin L, LNHR, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, TQ1, Pln homing receptor - Gen-ID
- 6402
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