L-Selectin Antikörper (FITC)

Produktnummer ABIN206072

Der Maus Monoklonal Anti-L-Selectin-Antikörper wurde für FACS, IHC, IP und IHC (fro) validiert. Er ist geeignet, L-Selectin in Proben von Human, Rind (Kuh), Cynomolgus und Rhesusaffen zu detektieren.

Kurzübersicht für L-Selectin Antikörper (FITC) (ABIN206072)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Human, Rind (Kuh), Cynomolgus, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser L-Selectin Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: FMC46

Produktdetails anti-L-Selectin Antikörper (FITC)

Spezifität: Recognizes human CD62L, also known a L-selectin, a 74-95kD member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naA-ve lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Aufreinigung: Protein G purified

Immunogen: PHA stimulated lymphoblasts.

Type of Immunogen: Cells

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:1), IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: SELL / L-Selectin / CD62L

Substanzklasse: Chemical

Hintergrund: Name/Gene ID: SELL

Synonyms: SELL, CD62L, CD62L antigen, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Lyam-1, LSEL, gp90-MEL, HLHRc, PLNHR, L-selectin, Leu-8, Selectin L, LNHR, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, TQ1, Pln homing receptor

Gen-ID: 6402