CXCR4 Antikörper (AA 1-14)
Kurzübersicht für CXCR4 Antikörper (AA 1-14) (ABIN204153)
Target
Alle CXCR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-14
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Spezifität
- CXCR4 associates with the surface CD4-gp120 complex before HIV enters target cells. CXCR4 messenger RNA levels correlated with HIV-1 permissiveness in diverse human cell types. Blocks HIV-1 and HIV-2 fusion and infection of human target cells. The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV binding sites.
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Aufreinigung
- Purified
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Immunogen
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Peptide corresponding to amino acids 1 to 14 of human CXCR4 (3,9).
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG
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Applikationshinweise
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Approved: ICC (10 μg/mL), IP (10 μg/mL), WB (1 - 2 μg/mL)
Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Western Blot: 1-2 μg/mL. Immunoprecipitation: 10 μg/mL. Immunocytochemistry: 10 μg/mL. Positive control: HeLa whole cell lysate. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS. No preservative added.
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Konservierungsmittel
- Azide free
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Andere Bezeichnung
- CXCR4
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Hintergrund
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Name/Gene ID: CXCR4
Subfamily: Chemokine
Family: GPCR
Synonyms: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR -
Gen-ID
- 7852
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UniProt
- P61073
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Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
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