Rabies Virus Nucleoprotein (RABV N) Antikörper

Produktnummer ABIN1993849

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Rabies Virus Nucleoprotein in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Rabies Virus.

Kurzübersicht für Rabies Virus Nucleoprotein (RABV N) Antikörper (ABIN1993849)

Target: Rabies Virus Nucleoprotein (RABV N)

Reaktivität: Rabies Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Aufreinigung: Caprylic Acid Ammonium Sulfate Precipitation

Immunogen: Recombinant Rabies virus Nucleoprotein protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working concentration should be determinde by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Upon delivery aliquot and store at -20 °C or -80 °C.

Antigendetails

Target: Rabies Virus Nucleoprotein (RABV N)

Andere Bezeichnung: Rabies Virus Nucleoprotein

Substanzklasse: Influenza Protein

Hintergrund: Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it\'s own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases
Synonyms: NP, Nucleocapsid protein, Protein N, N

UniProt: P15197