Haptoglobin Antikörper (FITC)

Produktnummer ABIN1992508

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Haptoglobin in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für Haptoglobin Antikörper (FITC) (ABIN1992508)

Target: Haptoglobin (HP)

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Haptoglobin Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Haptoglobin Antikörper (FITC)

Aufreinigung: Caprylic Acid Ammonium Sulfate Precipitation

Immunogen: Recombinant rat Haptoglobin protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working concentration should be determinde by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Upon delivery aliquot and store at -20 °C or -80 °C.

Details zu Haptoglobin

Target: Haptoglobin (HP)

Andere Bezeichnung: Haptoglobin

Hintergrund: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway?.Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Synonyms: Liver regeneration-related protein LRRG173, Zonulin,Hp,Ba1-647

UniProt: P06866

Pathways: Transition Metal Ion Homeostasis