CD101 Antikörper (PE)

Produktnummer ABIN1981894

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD101 in FACS. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für CD101 Antikörper (PE) (ABIN1981894)

Target: CD101

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD101 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: BB27

Produktdetails anti-CD101 Antikörper (PE)

Verwendungszweck: Anti-Hu CD101 PE

Kreuzreaktivität (Details): Human

Produktmerkmale: The mouse monoclonal antibody BB27 recognizes an extracellular epitope of CD101, a 140 kDa disulfide-bonded homodimeric protein expressed on activated T cells, and some other cell types, such as granulocytes and cells of the monocyte/macropgage lineage.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human thymic clone B12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze,Protect from prolonged exposure to light

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Referenzen für anti-CD101 Antikörper (PE) (ABIN1981894)

Grassi, Dezutter-Dambuyant, McIlroy, Jacquet, Yoneda, Imamura, Boumsell, Schmitt, Autran, Debré, Hosmalin: "Monocyte-derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules." in: Journal of leukocyte biology, Vol. 64, Issue 4, pp. 484-93, (1998) (PubMed).

Bagot, Martinel, Charue, Weill, Boulland, Wechsler, Freeman, Bensussan, Boumsell: "CD101 is expressed by skin dendritic cells. Role in T-lymphocyte activation." in: Tissue antigens, Vol. 50, Issue 5, pp. 439-48, (1998) (PubMed).

Details zu CD101

Target: CD101

Andere Bezeichnung: CD101

Hintergrund: CD101 Molecule,CD101 is a type I transmembrane glycoprotein, which forms disulfide-linked homodimers. It is expressed on activated T cells, as well as on granulocytes, monocytes, dendritic cells or mucosal T cells. It plays a major role in the activation of T cells by skin dendritic cells. Function of CD101 has not been fully elucidated, but in mice its knock-out results in liver autoimmune disease induced by Novosphingobium aromaticivorans.,IGSF2, V7, EWI-101

Gen-ID: 9398

UniProt: Q93033