CD300E Antikörper (PE)

Produktnummer ABIN1981891

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD300E in FACS. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für CD300E Antikörper (PE) (ABIN1981891)

Target: CD300E (CD300e Molecule (CD300E))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD300E Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: UP-H2

Produktdetails anti-CD300E Antikörper (PE)

Verwendungszweck: Anti-Hu CD300e PE

Kreuzreaktivität (Details): Human

Produktmerkmale: The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: CD300e-HA-transfected cells

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze,Protect from prolonged exposure to light

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Referenzen für anti-CD300E Antikörper (PE) (ABIN1981891)

Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." in: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

Aguilar, Alvarez-Errico, García-Montero, Orfao, Sayós, López-Botet: "Molecular characterization of a novel immune receptor restricted to the monocytic lineage." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6703-11, (2004) (PubMed).

Details zu CD300E

Target: CD300E (CD300e Molecule (CD300E))

Andere Bezeichnung: CD300e

Hintergrund: CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2

Gen-ID: 342510

UniProt: Q496F6