Hsc70 Antikörper (C-Term)
Kurzübersicht für Hsc70 Antikörper (C-Term) (ABIN1944844)
Target
Alle Hsc70 (HSPA8) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 539-569, C-Term
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Homologie
- B, Ha, Hs, M, Rat
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This HSPA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-569 amino acids from the C-terminal region of human HSPA8.
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Isotyp
- Ig Fraction
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Applikationshinweise
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70." in: Molecular pharmacology, Vol. 58, Issue 6, pp. 1257-63, (2000) (PubMed).
: "Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes." in: Biochemical and biophysical research communications, Vol. 224, Issue 3, pp. 666-74, (1996) (PubMed).
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: "Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70." in: Molecular pharmacology, Vol. 58, Issue 6, pp. 1257-63, (2000) (PubMed).
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- Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
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Andere Bezeichnung
- HSPA8
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Hintergrund
- HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. The protein also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell.
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Molekulargewicht
- 70898
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Gen-ID
- 3312
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NCBI Accession
- NP_006588, NP_694881
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UniProt
- P11142
Target
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