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Hsc70 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Hsc70 in WB, IF, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN1944844

Kurzübersicht für Hsc70 Antikörper (C-Term) (ABIN1944844)

Target

Alle Hsc70 (HSPA8) Antikörper anzeigen
Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Reaktivität

  • 89
  • 50
  • 43
  • 20
  • 16
  • 9
  • 8
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 91
  • 31
  • 5
  • 2
Kaninchen

Klonalität

  • 86
  • 42
Polyklonal

Konjugat

  • 75
  • 22
  • 15
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Hsc70 Antikörper ist unkonjugiert

Applikation

  • 116
  • 80
  • 54
  • 42
  • 39
  • 37
  • 17
  • 10
  • 10
  • 10
  • 9
  • 5
  • 4
  • 2
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB16528
  • Bindungsspezifität

    • 20
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 539-569, C-Term

    Homologie

    B, Ha, Hs, M, Rat

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This HSPA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-569 amino acids from the C-terminal region of human HSPA8.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Tsukahara, Yoshioka, Muraki: "Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70." in: Molecular pharmacology, Vol. 58, Issue 6, pp. 1257-63, (2000) (PubMed).

    Egerton, Moritz, Druker, Kelso, Simpson: "Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes." in: Biochemical and biophysical research communications, Vol. 224, Issue 3, pp. 666-74, (1996) (PubMed).

  • Target

    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

    Andere Bezeichnung

    HSPA8

    Hintergrund

    HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. The protein also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell.

    Molekulargewicht

    70898

    Gen-ID

    3312

    NCBI Accession

    NP_006588, NP_694881

    UniProt

    P11142
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