MAD2L1 Antikörper

Produktnummer ABIN1944831

Dieses Anti-MAD2L1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MAD2L1 in WB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für MAD2L1 Antikörper (ABIN1944831)

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAD2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAD2L1 Antikörper

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-MAD2L1 Antikörper (ABIN1944831)

Gemma, Hosoya, Seike, Uematsu, Kurimoto, Hibino, Yoshimura, Shibuya, Kudoh, Emi: "Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers." in: Lung cancer (Amsterdam, Netherlands), Vol. 32, Issue 3, pp. 289-95, (2001) (PubMed).

Details zu MAD2L1

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Andere Bezeichnung: MAD2L1

Hintergrund: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore- spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

Molekulargewicht: 23510 Da

Gen-ID: 4085

UniProt: Q13257