Der Kaninchen Polyklonal Anti-Prostacyclin Receptor-Antikörper wurde für WB und IF validiert. Er ist geeignet, Prostacyclin Receptor in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.
PTGIR
Reaktivität: Human
WB, IHC, ICC, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
IF: 1:100. WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Lagerung
4 °C,-20 °C
Ogawa, Tanaka, Inoue, Yoshitake, Isse, Nakagawa, Usui, Itoh, Yoshimasa, Narumiya: "Structural organization and chromosomal assignment of the human prostacyclin receptor gene." in: Genomics, Vol. 27, Issue 1, pp. 142-8, (1995) (PubMed).
Boie, Rushmore, Darmon-Goodwin, Grygorczyk, Slipetz, Metters, Abramovitz: "Cloning and expression of a cDNA for the human prostanoid IP receptor." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 12173-8, (1994) (PubMed).
Katsuyama, Sugimoto, Namba, Irie, Negishi, Narumiya, Ichikawa: "Cloning and expression of a cDNA for the human prostacyclin receptor." in: FEBS letters, Vol. 344, Issue 1, pp. 74-8, (1994) (PubMed).
Nakagawa, Tanaka, Usui, Harada, Sasaki, Itoh, Yoshimasa, Namba, Narumiya, Nakao: "Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system." in: Circulation, Vol. 90, Issue 4, pp. 1643-7, (1994) (PubMed).
Target
Prostacyclin Receptor (PTGIR)
Andere Bezeichnung
Prostacyclin Receptor
Hintergrund
Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.