ADCY9 Antikörper

Produktnummer ABIN1944823

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ADCY9 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für ADCY9 Antikörper (ABIN1944823)

Target: ADCY9 (Adenylate Cyclase 9 (ADCY9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADCY9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ADCY9 Antikörper

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-ADCY9 Antikörper (ABIN1944823)

Tantisira, Small, Litonjua, Weiss, Liggett: "Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways." in: Human molecular genetics, Vol. 14, Issue 12, pp. 1671-7, (2005) (PubMed).

Small, Brown, Theiss, Seman, Weiss, Liggett: "An Ile to Met polymorphism in the catalytic domain of adenylyl cyclase type 9 confers reduced beta2-adrenergic receptor stimulation." in: Pharmacogenetics, Vol. 13, Issue 9, pp. 535-41, (2003) (PubMed).

Hacker, Tomlinson, Wayman, Sultana, Chan, Villacres, Disteche, Storm: "Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9)." in: Genomics, Vol. 50, Issue 1, pp. 97-104, (1999) (PubMed).

Details zu ADCY9

Target: ADCY9 (Adenylate Cyclase 9 (ADCY9))

Andere Bezeichnung: ADCY9

Hintergrund: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).

Molekulargewicht: 150701 Da

Gen-ID: 115

UniProt: O60503

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma