Annexin a1 Antikörper

Produktnummer ABIN1944802

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Annexin a1 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für Annexin a1 Antikörper (ABIN1944802)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Annexin a1 Antikörper

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-Annexin a1 Antikörper (ABIN1944802)

Arcone, Arpaia, Ruoppolo, Malorni, Pucci, Marino, Ialenti, Di Rosa, Ciliberto: "Structural characterization of a biologically active human lipocortin 1 expressed in Escherichia coli." in: European journal of biochemistry / FEBS, Vol. 211, Issue 1-2, pp. 347-55, (1993) (PubMed).

Kovacic, Tizard, Cate, Frey, Wallner: "Correlation of gene and protein structure of rat and human lipocortin I." in: Biochemistry, Vol. 30, Issue 37, pp. 9015-21, (1991) (PubMed).

Varticovski, Chahwala, Whitman, Cantley, Schindler, Chow, Sinclair, Pepinsky: "Location of sites in human lipocortin I that are phosphorylated by protein tyrosine kinases and protein kinases A and C." in: Biochemistry, Vol. 27, Issue 10, pp. 3682-90, (1988) (PubMed).

Biemann, Scoble: "Characterization by tandem mass spectrometry of structural modifications in proteins." in: Science (New York, N.Y.), Vol. 237, Issue 4818, pp. 992-8, (1987) (PubMed).

Wallner, Mattaliano, Hession, Cate, Tizard, Sinclair, Foeller, Chow, Browing, Ramachandran: "Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity." in: Nature, Vol. 320, Issue 6057, pp. 77-81, (1986) (PubMed).

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: ANXA1

Hintergrund: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.

Molekulargewicht: 38714 Da

Gen-ID: 301

UniProt: P04083

Pathways: Hormone Transport