MAFK Antikörper

Produktnummer ABIN1944786

Zitiert in 2+ Publikationen. Der Maus Monoklonal anti-MAFK Antikörper (Klon 1328CT786-105-125) (ABIN1944786) detektiert spezifisch MAFK in WB und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MAFK Antikörper (ABIN1944786)

Target: MAFK (Transcription Factor MafK (MAFK))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAFK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: 1328CT786-105-125

Produktdetails anti-MAFK Antikörper

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This MAFK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human MAFK.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-MAFK Antikörper (ABIN1944786)

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).

Toki, Itoh, Kitazawa, Arai, Hatakeyama, Akasaka, Igarashi, Nomura, Yokoyama, Yamamoto, Ito: "Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif." in: Oncogene, Vol. 14, Issue 16, pp. 1901-10, (1997) (PubMed).

Details zu MAFK

Target: MAFK (Transcription Factor MafK (MAFK))

Andere Bezeichnung: MAFK

Hintergrund: Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

Molekulargewicht: 17523

Gen-ID: 7975

UniProt: O60675