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PLSCR1 Antikörper

Dieses Anti-PLSCR1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PLSCR1 in WB, IP, FACS und ICC. Geeignet für Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN192390

Kurzübersicht für PLSCR1 Antikörper (ABIN192390)

Target

Alle PLSCR1 Antikörper anzeigen
PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

Reaktivität

  • 27
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 19
  • 9
Maus

Klonalität

  • 19
  • 9
Monoklonal

Konjugat

  • 28
Dieser PLSCR1 Antikörper ist unkonjugiert

Applikation

  • 25
  • 11
  • 9
  • 8
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon

13A6 [TEC-23]
  • Verwendungszweck

    Anti-Rt PLSCR1 Ascites

    Spezifität

    The antibody 13A6 [TEC-23] binds to an intracellular epitope of rat Phospholipid Scramblase 1 (PLSCR1), an 37-49 kDa protein, accelerating bidirectional movement of plasma membrane phospholipids under conditions of elevated calcium.

    Kreuzreaktivität (Details)

    Rat

    Immunogen

    Pooled lipid raft fraction isolated from RBL-2H3 cells

    Isotyp

    IgG2a
  • Applikationshinweise

    Western blotting: Recommended dilution: 1 μg/mL, positive control: RBL (rat basophilic leukemia) cell line, both reducing and non-reducing conditions.
    Flow cytometry: Intracellular staining.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Stabilized with 15 mM sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.
    Avoid prolonged exposure to light.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Do not freeze.
  • Smrz, Lebduska, Dráberová, Korb, Dráber: "Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10904-18, (2008) (PubMed).

  • Target

    PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

    Andere Bezeichnung

    PLSCR1

    Hintergrund

    Phospholipid scramblase 1,PLSCR1 (phospholipid scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.,PL scramblase 1, phospholipid scramblase 1

    Gen-ID

    117540

    UniProt

    P58195

    Pathways

    Cellular Response to Molecule of Bacterial Origin
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