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CD177 Antikörper (PE)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD177 in FACS. Er zeigt eine Reaktivität gegenüber Human und Non-Human Primate.
Produktnummer ABIN192244

Kurzübersicht für CD177 Antikörper (PE) (ABIN192244)

Target

Alle CD177 Antikörper anzeigen
CD177 (CD177 Molecule (CD177))

Reaktivität

  • 56
  • 8
  • 5
  • 4
  • 3
  • 3
  • 3
Human, Non-Human Primate

Wirt

  • 36
  • 25
  • 1
Maus

Klonalität

  • 39
  • 23
Monoklonal

Konjugat

  • 34
  • 7
  • 6
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD177 Antikörper ist konjugiert mit PE

Applikation

  • 37
  • 23
  • 18
  • 18
  • 12
  • 9
  • 5
  • 4
  • 2
  • 1
  • 1
Flow Cytometry (FACS)

Klon

MEM-166
  • Verwendungszweck

    Anti-Hu CD177 PE

    Spezifität

    The antibody MEM-166 reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.

    Kreuzreaktivität (Details)

    Non-Human Primates, Human

    Aufreinigung

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    Human granulocytes

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Rekonstitution

    No reconstitution is necessary.

    Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.
    Avoid prolonged exposure to light.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target

    CD177 (CD177 Molecule (CD177))

    Andere Bezeichnung

    CD177

    Hintergrund

    CD177 Molecule,CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).,NB1, PRV1, HNA2A

    Gen-ID

    57126

    UniProt

    Q8N6Q3
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