CD58 Antikörper (PE)
Kurzübersicht für CD58 Antikörper (PE) (ABIN192150)
Target
Alle CD58 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD58 PE
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Spezifität
- The antibody MEM-63 reacts with CD58 (LFA-3), a 40-70 kDa extracellular membrane glycoprotein distributed over many tissues, leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts.
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Kreuzreaktivität (Details)
- Porcine, Human
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Aufreinigung
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogen
- NALM-6 human pre-B cell line
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Isotyp
- IgG1
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Applikationshinweise
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- No reconstitution is necessary.
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Buffer
- Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
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Do not freeze.
Avoid prolonged exposure to light. -
Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- CD58
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Andere Bezeichnung
- CD58
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Hintergrund
- CD58 Molecule,CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form, the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.,LFA3, AG3
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Gen-ID
- 965
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UniProt
- P19256
Target
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