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IBSP Antikörper (Native Form)

Dieses Anti-IBSP-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IBSP in WB, IHC (p), EIA, IF, RIA und IHC (fro). Geeignet für Human.
Produktnummer ABIN191977

Kurzübersicht für IBSP Antikörper (Native Form) (ABIN191977)

Target

Alle IBSP Antikörper anzeigen
IBSP (Integrin-Binding Sialoprotein (IBSP))

Reaktivität

  • 52
  • 11
  • 9
  • 2
  • 1
Human

Wirt

  • 48
  • 3
  • 2
  • 1
  • 1
Maus

Klonalität

  • 50
  • 5
Monoklonal

Konjugat

  • 28
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IBSP Antikörper ist unkonjugiert

Applikation

  • 46
  • 18
  • 13
  • 13
  • 11
  • 9
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF), Radioimmunoassay (RIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon

ID1-2
  • Bindungsspezifität

    • 15
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Native Form

    Spezifität

    This antibody recognizes Human Bone Sialoprotein, Recombinant Human, Recombinant Porcine and Recombinant Rat BSP. There was no cross reactivity obtained with Human, Porcine Osteonectin and Osteopontin.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human, Porcine, Rat.

    Produktmerkmale

    Synonyms: Bone sialoprotein II, BSP II, IBSP, BNSP, Cell-binding sialoprotein, Integrin-bindingsialoprotein

    Aufreinigung

    Protein G Chromatography

    Immunogen

    Human Bone Sialoprotein (Bone extract).

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA (3). RIA. Western blot: 1/1000 (1,3). Immunocytochemstry: 1/200 (3). Immunohistochemistry on CryoSections, Resin-Embedded Sections: 1/100 (2,3,5,6). Immunohistochemistry on Paraffin Sections: 1/2000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Rekonstitution

    Restore in aqua bidest to 1 mg/mL.

    Buffer

    50 mM TRIS, pH 7.4

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.

    Haltbarkeit

    12 months
  • Target

    IBSP (Integrin-Binding Sialoprotein (IBSP))

    Andere Bezeichnung

    Bone Sialoprotein 2

    Hintergrund

    The protein encoded by the Bone Sialoprotein gene is a major structural protein of the bone matrix. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts, and it constitutes approximately 12 % of the noncollagenous proteins in human bone. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.Synonyms: BNSP, BSP II, Bone sialoprotein II, Cell-binding sialoprotein, IBSP, Integrin-binding sialoprotein

    Gen-ID

    3381

    UniProt

    P21815
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