IBSP Antikörper

Produktnummer ABIN191813

Dieses Huhn Polyklonal-Antikörper erkennt spezifisch IBSP in WB, IHC (p), EIA, IF, RIA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IBSP Antikörper (ABIN191813)

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser IBSP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF), Radioimmunoassay (RIA), Flow Cytometry (FACS)

Produktdetails anti-IBSP Antikörper

Spezifität: This antibody detects Bone Sialoprotein. There were no cross reactivities obtained with Human Osteonectin, Human Osteopontin and Human Alkaline Phosphatase.

Aufreinigung: Purified

Immunogen: Human Bone Sialoprotein (bone extract)

Anwendungsinformationen

Applikationshinweise: ELISA (1 μg/mL). RIA (20 ng/mL). Flow Cytometry. Western blot (2 ng/mL). Immunohistochemistry on Paraffin Sections (2 ng/mL). Immunocytochemistry (1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in aqua bidest to initial volume.

Buffer: PBS, pH 7.4 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C and reconstituted at -20 °C.

Details zu IBSP

Target: IBSP (Integrin-Binding Sialoprotein (IBSP))

Andere Bezeichnung: Bone Sialoprotein 2

Hintergrund: The protein encoded by the Bone Sialoprotein gene is a major structural protein of the bone matrix. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts, and it constitutes approximately 12 % of the noncollagenous proteins in human bone. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.Synonyms: BNSP, BSP II, Bone sialoprotein II, Cell-binding sialoprotein, IBSP, Integrin-binding sialoprotein

Gen-ID: 3381

NCBI Accession: NP_004958

UniProt: P21815