Calcineurin A Antikörper (AA 264-283)
Kurzübersicht für Calcineurin A Antikörper (AA 264-283) (ABIN190682)
Target
Alle Calcineurin A (CAN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 264-283
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Verwendungszweck
- Anti-Calcineurin A (Catalytic) Rabbit Polyclonal Antibody
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Kreuzreaktivität
- Rind (Kuh), Hund, Hamster, Human, Maus, Kaninchen, Ratte
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Aufreinigung
- Affinity - Purified
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Immunogen
- Synthetic peptide corresponding to aa 264-283 of human Calcineurin A conjugated to KLH. This sequence is identical in rat and mouse calcineurin A.
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Applikationshinweise
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Immunoblotting: Use at 1-5 μg/mL. A band of ~61 kDa is detected.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Rekonstitution
- Dilute in PBS or medium that is identical to that used in the assay system.
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Konzentration
- Lot specific
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Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- This antibody is stable for at least one (1) year at -20°C.
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- Calcineurin A (CAN)
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Andere Bezeichnung
- Calcineurin A
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Hintergrund
- Serine/threonine-protein phosphatase 2B catalytic subunit α isoform,Calcineurin is a Ca+2/calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit and a myristylated regulatory B subunit that binds calcium. It controls the translocation of nuclear factors from the cytosol into the nucleus of activated T cells. Calcineurin is a target of immunosuppressive drugs such as cyclosporin A and FK506.,EC 3.1.3.16, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit α isoform
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Gen-ID
- 5530
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NCBI Accession
- NP_000935
Target
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