Influenza A Matrix Protein 2 Antikörper (Influenza A Virus H5N1) (N-Term)

Produktnummer ABIN1887830

Der Kaninchen Polyklonal Anti--Antikörper wurde für ELISA und WB validiert. Er ist geeignet, in Proben von Influenza A Virus H5N1 zu detektieren.

Kurzübersicht für Influenza A Matrix Protein 2 Antikörper (Influenza A Virus H5N1) (N-Term) (ABIN1887830)

Target: Influenza A Matrix Protein 2 (M2)

Reaktivität: Influenza A Virus H5N1

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: N-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 13 amino acid peptide from amino terminus of H5N1 M2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Antigendetails

Target: Influenza A Matrix Protein 2 (M2)

Substanzklasse: Influenza Protein

Hintergrund: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA.Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics.Influenza A can exist in a variety of animals, however, it is in birds that all subtypes can be found.These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes.During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong.The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia.There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low.The influenza membrane ion channel (M2) is a small transmembrane protein that regulates the pH inside the virion during viral entry into the cell and protects the newly synthesized hemagglutinin during their transport through low pH cellular compartments.It has been suggested as a target of neutralizing antibodies.
Synonyms: Avian Influenza A M2, H5N1 M2, H5N1 membrane ion channel 2