ACIN1 Antikörper (AA 994-1009)

Produktnummer ABIN1886906

Der Kaninchen Polyklonal anti-ACIN1 Antikörper wird verwendet zum Nachweis von ACIN1 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für ACIN1 Antikörper (AA 994-1009) (ABIN1886906)

Target: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ACIN1 Antikörper

Bindungsspezifität: AA 994-1009

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 994 to 1009 of human AcinusL, 267 to 282 of human AcinusS

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ACIN1

Target: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Andere Bezeichnung: Acinus

Hintergrund: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis.CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE.A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus).Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei.Acinus also induces apoptotic chromatin condensation in cells.Acinus is ubiquitously expressed.Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.

Molekulargewicht: 220 kDa