FEM1B Antikörper (AA 609-622)

Produktnummer ABIN1886892

Dieses Anti-FEM1B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FEM1B in ELISA, WB und IHC. Geeignet für Human, Ratte und Maus.

Kurzübersicht für FEM1B Antikörper (AA 609-622) (ABIN1886892)

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FEM1B Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FEM1B Antikörper

Bindungsspezifität: AA 609-622

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 609 to 622 of human F1A alpha.This sequence is identical to the corresponding sequence of mouse FEM1b.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu FEM1B

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Andere Bezeichnung: F1A alpha

Hintergrund: Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family.A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1beta.F1Aalpha/FEM1beta is the homologue of C.elegans sex determining protein FEM-1.FEM-1/F1Aalpha is cleaved by CED-3 and caspase.FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1.Overexpression of F1Aalpha induces apoptosis.F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis.F1Aalpha is expressed in a variety of human and mouse tissues.
Synonyms: F1A alpha

Molekulargewicht: 70 kDa