DNASE2 Antikörper (AA 347-360)

Produktnummer ABIN1886871

Dieses Anti-DNASE2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DNASE2 in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für DNASE2 Antikörper (AA 347-360) (ABIN1886871)

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DNASE2 Antikörper

Bindungsspezifität: AA 347-360

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 347 to 360 of human DNase II precursor (2-4).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu DNASE2

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Andere Bezeichnung: DNase II

Hintergrund: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation.These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus.DNase II causes both chromatin condensation and DNA fragmentation.The genes encoding human, porcine, and murine DNase II have been cloned.The DNase II gene encodes a 40 kDa proenzyme.The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing.Overexpression of DNase II induces chromatin condensation.DNase II is ubiquitously expressed in human tissues.
Synonyms: DNase II

Molekulargewicht: 40 kDa