RYBP Antikörper (AA 215-228)

Produktnummer ABIN1886857

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RYBP in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für RYBP Antikörper (AA 215-228) (ABIN1886857)

Target: RYBP (RING1 and YY1 Binding Protein (RYBP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RYBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-RYBP Antikörper

Bindungsspezifität: AA 215-228

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to amino acids 215 to 228 of human DEDAF the sequence is identical to that of mouse origin.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu RYBP

Target: RYBP (RING1 and YY1 Binding Protein (RYBP))

Andere Bezeichnung: DEDAF

Hintergrund: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules.Several molecules including caspases and adaptor FADD contain DEDs.A novel protein that interacts with DED of caspase-8 and 10, and FADD was identified recently and designated DEDAF for DED associated factor.DEDAF is identical to the transcriptional repressor RYBP.DEDAF/RYBP is expressed in multiple tissues and cell lines.DEDAF interacts with FADD and augments the formation of CD95/FADD/capase-8 complexes at the cell membrane, and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.

Molekulargewicht: 32 kDa