CIDEA Antikörper (AA 200-217)

Produktnummer ABIN1886854

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CIDEA in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CIDEA Antikörper (AA 200-217) (ABIN1886854)

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIDEA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CIDEA Antikörper

Bindungsspezifität: AA 200-217

Kreuzreaktivität (Details): It has no cross activity to CIDE-B.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 200 to 217 of human CIDE-A.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Andere Bezeichnung: CIDE-A

Hintergrund: Apoptosis is related to many diseases and induced by a family of cell death receptors.Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases.These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD.DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified.CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD.Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45.CIDE-A is expressed in many tissues.

Molekulargewicht: 23 kDa