Arc Antikörper (AA 2-18)

Produktnummer ABIN1886849

Der Kaninchen Polyklonal Anti-Arc-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Arc in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Arc Antikörper (AA 2-18) (ABIN1886849)

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Arc Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Arc Antikörper

Bindungsspezifität: AA 2-18

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 2 to 18 of human origin these sequences are identical to those of human nuclear protein Nop30 (2) and differ from those of the rat homolog of ARC by one amino acid (3).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu Arc

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Andere Bezeichnung: ARC

Hintergrund: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2.A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD.ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8.ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3.The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
Synonyms: ARC

Molekulargewicht: 25 kDa

NCBI Accession: NP_003937