IPO7 Antikörper (AA 976-1038)

Produktnummer ABIN1886728

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IPO7 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IPO7 Antikörper (AA 976-1038) (ABIN1886728)

Target: IPO7 (Importin 7 (IPO7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IPO7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-IPO7 Antikörper

Bindungsspezifität: AA 976-1038

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 976 and 1038 of Importin-7

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 x PBS, 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu IPO7

Target: IPO7 (Importin 7 (IPO7))

Andere Bezeichnung: Importin-7

Hintergrund: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal.The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta.Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin.This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions.At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.[provided by RefSeq]

Molekulargewicht: 120 kDa

Gen-ID: 10527

NCBI Accession: NM_006391, NP_006382

Pathways: Protein targeting to Nucleus