UGT1A6 Antikörper (AA 8-187)

Produktnummer ABIN1886667

Dieses Anti-UGT1A6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UGT1A6 in WB und IHC. Geeignet für Human.

Kurzübersicht für UGT1A6 Antikörper (AA 8-187) (ABIN1886667)

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT1A6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-UGT1A6 Antikörper

Bindungsspezifität: AA 8-187

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 8 and 187 (P19224) of UGT1A6

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu UGT1A6

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Andere Bezeichnung: UGT1A6

Hintergrund: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites.This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases.The locus includes thirteen unique alternate first exons followed by four common exons.Four of the alternate first exons are considered pseudogenes.Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini.Each first exon encodes the substrate binding site, and is regulated by its own promoter.The enzyme encoded by this gene is active on phenolic and planar compounds.Alternative splicing in the unique 5' end of this gene results in two transcript variants.[provided by RefSeq]

Molekulargewicht: 61 kDa

Gen-ID: 54578

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha