POLG Antikörper (AA 779-1191)
Kurzübersicht für POLG Antikörper (AA 779-1191) (ABIN1886660)
Target
Alle POLG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 779-1191
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Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 779 and 1191 (P54098) of DNA polymerase gamma
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Applikationshinweise
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- POLG (Polymerase (DNA Directed), gamma (POLG))
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Andere Bezeichnung
- DNA Polymerase gamma
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Hintergrund
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Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit.The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase.The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic.Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE).Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq]
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Molekulargewicht
- 140 kDa
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Gen-ID
- 5428
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NCBI Accession
- NM_002693, NP_002684
Target
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