RASA3
Reaktivität: Human, Maus, Ratte
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 750
Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
1 x PBS, 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
RASA3
(RAS P21 Protein Activator 3 (RASA3))
Andere Bezeichnung
RASA3
Hintergrund
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins.The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart.Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation.This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2.The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.[provided by RefSeq]