Ubiquilin 1 Antikörper (AA 64-315)

Produktnummer ABIN1886597

Der Kaninchen Polyklonal Anti-Ubiquilin 1-Antikörper wurde für WB und IF validiert. Er ist geeignet, Ubiquilin 1 in Proben von Human zu detektieren.

Kurzübersicht für Ubiquilin 1 Antikörper (AA 64-315) (ABIN1886597)

Target: Ubiquilin 1 (UBQLN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ubiquilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Ubiquilin 1 Antikörper

Bindungsspezifität: AA 64-315

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 64 and 315 of Ubiquilin-1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Ubiquilin 1

Target: Ubiquilin 1 (UBQLN1)

Andere Bezeichnung: Ubiquilin-1

Hintergrund: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog.Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain.They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation.This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Molekulargewicht: 63 kDa

Gen-ID: 29979

NCBI Accession: NP_038466, NM_013438