CKMT1B Antikörper (AA 63-297)

Produktnummer ABIN1886588

Der Kaninchen Polyklonal Anti-CKMT1B-Antikörper wurde für WB und IHC validiert. Er ist geeignet, CKMT1B in Proben von Human zu detektieren.

Kurzübersicht für CKMT1B Antikörper (AA 63-297) (ABIN1886588)

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKMT1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CKMT1B Antikörper

Bindungsspezifität: AA 63-297

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 63 and 297 of Human CKMT1B

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu CKMT1B

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Andere Bezeichnung: Creatine kinase(mitochondrial 1B)

Hintergrund: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine.It belongs to the creatine kinase isoenzyme family.It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes.Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes.Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis.Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.[provided by RefSeq]
Synonyms: CKMT, CKMT1, UMTCK

Molekulargewicht: 47 kDa

Gen-ID: 1159

NCBI Accession: NP_066270, NM_020990