Haptoglobin Antikörper (AA 57-392)

Produktnummer ABIN1886560

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Haptoglobin in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Haptoglobin Antikörper (AA 57-392) (ABIN1886560)

Target: Haptoglobin (HP)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Haptoglobin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Haptoglobin Antikörper

Bindungsspezifität: AA 57-392

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 57 and 392 of Haptoglobin

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Haptoglobin

Target: Haptoglobin (HP)

Andere Bezeichnung: Haptoglobin

Hintergrund: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin.Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin.Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia.This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria.A similar duplicated gene is located next to this gene on chromosome 16.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Molekulargewicht: 45 kDa

Gen-ID: 3240

NCBI Accession: NP_005134, NM_005143

Pathways: Transition Metal Ion Homeostasis