Acetylcholinesterase Antikörper (AA 551-614)

Produktnummer ABIN1886552

Der Kaninchen Polyklonal Anti-Acetylcholinesterase-Antikörper wurde für WB und IF validiert. Er ist geeignet, Acetylcholinesterase in Proben von Human zu detektieren.

Kurzübersicht für Acetylcholinesterase Antikörper (AA 551-614) (ABIN1886552)

Target: Acetylcholinesterase (AChE)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetylcholinesterase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Acetylcholinesterase Antikörper

Bindungsspezifität: AA 551-614

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 551 and 614 of Human ACHE

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Acetylcholinesterase

Target: Acetylcholinesterase (AChE)

Andere Bezeichnung: AChE

Hintergrund: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission.It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen.Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface.It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits.The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site.It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.[provided by RefSeq]

Molekulargewicht: 68 kDa

Gen-ID: 43

NCBI Accession: NP_000656, NM_000665

Pathways: Skeletal Muscle Fiber Development