SAFB Antikörper (AA 476-705)

Produktnummer ABIN1886502

Der Kaninchen Polyklonal anti-SAFB Antikörper (ABIN1886502) detektiert spezifisch SAFB in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SAFB Antikörper (AA 476-705) (ABIN1886502)

Target: SAFB (Scaffold Attachment Factor B (SAFB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-SAFB Antikörper

Bindungsspezifität: AA 476-705

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 476 and 705 of HET/ SAF B

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu SAFB

Target: SAFB (Scaffold Attachment Factor B (SAFB))

Andere Bezeichnung: HET/ SAF B

Hintergrund: This gene encodes a DNA-binding protein that has highfor scaffold or matrix attachment region DNA elements (S/MAR DNA).This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein.Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR.This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes.It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor.This gene is a candidate gene for breast tumorigenesis.[provided by RefSeq]

Molekulargewicht: 103 kDa

Gen-ID: 6294

NCBI Accession: NM_002967, NP_002958

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway