PUF60 Antikörper (AA 346-533)

Produktnummer ABIN1886388

Dieses Anti-PUF60-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PUF60 in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für PUF60 Antikörper (AA 346-533) (ABIN1886388)

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PUF60 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PUF60 Antikörper

Bindungsspezifität: AA 346-533

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 533 of Human PUF60

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu PUF60

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Andere Bezeichnung: PUF60

Hintergrund: The protein encoded by this gene is a Ro RNP-binding protein.It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs.This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein.It can repress a c-myc reporter via the FUSE.It is also known to target transcription factor IIH and inhibit activated transcription.This gene is implicated in the xeroderma pigmentosum disorder.There are two alternatively spliced transcript variants of this gene encoding different isoforms.There seems to be evidence of multiple polyadenylation sites for this gene.[provided by RefSeq]
Synonyms: FIR, PUF60, RoBPI

Molekulargewicht: 58 kDa

Gen-ID: 22827

NCBI Accession: NP_055096, NM_014281