Coagulation Factor X Antikörper (AA 33-282)

Produktnummer ABIN1886374

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Coagulation Factor X in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Coagulation Factor X Antikörper (AA 33-282) (ABIN1886374)

Target: Coagulation Factor X (F10)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coagulation Factor X Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Coagulation Factor X Antikörper

Bindungsspezifität: AA 33-282

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 33 and 282 of Human F10

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Coagulation Factor X

Target: Coagulation Factor X (F10)

Andere Bezeichnung: Factor X

Hintergrund: This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade.This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR.Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases.The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway).The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.[provided by RefSeq]

Molekulargewicht: 55 kDa

Gen-ID: 2159

NCBI Accession: NM_000504, NP_000495