WT1 Antikörper (AA 277-495)

Produktnummer ABIN1886304

Dieses Anti-WT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von WT1 in IHC, IF und WB. Geeignet für Human.

Kurzübersicht für WT1 Antikörper (AA 277-495) (ABIN1886304)

Target: WT1 (Wilms Tumor 1 (WT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB)

Produktdetails anti-WT1 Antikörper

Bindungsspezifität: AA 277-495

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 277 and 495 (P19544) of Wilms Tumor 1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Andere Bezeichnung: WT1

Hintergrund: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus.It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors.Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized.There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.[provided by RefSeq]

Molekulargewicht: 56 kDa

Gen-ID: 7490

NCBI Accession: NM_024426, NP_077744

Pathways: Tube Formation